International Journal of Drug Research and Technology

A STUDY ON ANTIOXIDANT ACTIVITY OF FRUIT EXTRACTS OF COCCINIA GRANDIS L.VOIGT

Abstract

Deshpande S.V.*,PatilM.J., Parmar K.K.,Daswadkar S.C. and Khodade R.B.

T

he

aim of the present study was

investigating the antioxidant activity of the methanolic extract of the fruit

of

Coccinia grandis

L. Voigt.

(Cucurbitaceae). The antioxidant

activity of the fruit

has

been evaluated by

using three

in vitro

assays and was

com

pared to standard antioxidant

,

Butylated

h

ydroxy

a

nisole

(BH

A

).

All the fractions showed effective H

-

donor activity, reducing power, free radical scavenging activity. The

antioxidant property depends upon concentration and increased with increasing amount o

f the fractions.

The free radical scavenging and antioxidant activities may be attributed to the presence of flavonoid

s

present in the fractions. The results obtained in the present study indicate that the fruit of

Coccinia grandis

i

s

a potential source of

natural antioxidant.