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Enzyme-Mediated Interactions between Drugs and Herbs

Abstract

Abdulaziz Alhossan*

Despite the fact that herbal remedies have been used for more than 5000 years, in earlier times, only single herbs were consumed. Nowadays, herbal remedies are used frequently, particularly by women and patients with chronic conditions. Herbal supplements are used by approximately 15% to 20% of people who take prescription medications. However, even if they experience severe side effects, they may be reluctant to tell their doctors about their personal use of herbal medicines for fear of reprisal. This is especially important for the elderly, the frail and people who take multiple medications for chronic diseases have been linked to clinically significant adverse drug reactions. Ginkgo products taken with aspirin, warfarin (Coumadin), or ticlopidine (Ticlid) can cause bleeding when they interact with one another. Additionally, taking antidepressants alongside St. John's wort (SJW) can result in allergic reactions and gastrointestinal issues.

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