International Journal of Drug Research and Technology

EXTRACTION AND ISOLATION OF MELANIN FROM ACTINOMYCETES

Abstract

Shreya Modi, Poonam B Chauhan, Mayur Gahlout and Hiren Prajapati

Twenty different isolates of actinomycetes collected from different localities in Valsad, were screened for melanin pigment production and isolate S1 found to be highest producer of melanin. At 30˚C melanin pigment was produced and confirmed using L-DOPA (as substrate) optimum carbon and nitrogen for melanin production was found to be 10.4 and 31.3 respectively. Melanin was successfully extracted in a crude form and used for the antimicrobial activity against selected microorganism.