Mini-Review
AN APPROACH TO ENHANCING THE BIOAVAILABILITY, DISSOLUTION, AND SOLUBILITY OF DRUGS
Author(s): Eliza Mac*
Pharmaceutical particle technology is used to improve drug compounds' low dissolution rate in the gastrointestinal fluids following oral administration, which limits their bioavailability due to their poor aqueous solubility. The molecule innovation includes a few methodologies from the regular size decrease cycles to the more up to date, novel molecule innovations that change the dissolvability properties of the medications and produce strong, powdered type of the medications that are promptly solvent in water and can be effectively formed into different measurement structures. The solid particle technologies that can be used to improve the aqueous solubility, dissolution, and bioavailability of drugs are highlighted in this overview. Solubility, dissolution, and gastrointestinal permeability are fundamental parameters that control the rate and extent of drug absorption as well as it.. Read More»
DOI:
10.37421/2277-1506.2022.11.366